Systematic review of melatonin treatment in children with neurodevelopmental disabilities and sleep impairment

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Systematic review of melatonin treatment in children with neurodevelopmental disabilities and sleep impairment.

Sleep disturbances in children with neurodevelopmental disabilities are common and frequently difficult to treat with conventional pharmacological and behavioural methods. Melatonin is a pineal hormone known to be important in the regulation of the circadian rhythm, including the sleep-wake cycle. This systematic review of available evidence from randomized clinical trials assesses whether mela...

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ژورنال

عنوان ژورنال: Developmental Medicine & Child Neurology

سال: 2007

ISSN: 0012-1622,1469-8749

DOI: 10.1111/j.1469-8749.2004.tb00998.x